2002 2003 2004 2005 2006 2007 2008


January 8 (9:00 to 10:30) Laila's research review

January 15 (9:00 to 10:30) Laila on E. Ahissar & A. Arieli (2001) Figuring space by time, Neuron 32 : 185-201 (October 25 issue)

January 22 (9:00 to 10:30) Sharif

January 29 (9:00 to 10:30) Laila continues with E. Ahissar et al (1997) Decoding temporally encoded sensory input by cortical oscillations and thalamic phase comparators. PNAS 94:11633-11638 ; E. Ahissar et al. (2000) Transformation from temporal to rate coding in a somatosensory cortical pathway. Nature 406: 302-305 ; Review E. Ahissar (1998) Temporal-code to rate-code conversion by neuronal phase-locked loops. Neural Computation 10:597-650

January 30 (9:00 to 10:00) Laila continues with E. Ahissar .... And will finish!!!

Feb 5 (9:00 to 10:30) Cancelled--Stryker away

Feb 12 (9:00 to 10:30) Patrick

Feb 19 (9:00 to 10:30) Cancelled--Stryker away

Feb 26 (9:00 to 10:30) Cancelled--Stryker away


Mar 12 (10:00 to 11:00) Yoshio Hata will discuss a new experiment and some of his recent results from Osaka

VISIT (1) Yoshio Hata and Katsuro Kameyama, March 11-15

Mar 15 (11:00 to 12:00) Beata Gierdalska-Jablonska will discuss (1) her doctoral studies on "Effects of NMDA receptor blockade on plastic changes in the adult barrel field of mice" and (2) her current work at the NIH on "The effect of layer 4 disruption on GABAergic system in ferret"

Mar 19 -- CANCELLED -- sorry

Mar 26 -- Moved to March 28

Mar 28 THURSDAY (9:00 to 10:30) Open


Naoum Issa visit , April 13-20

Apr 9 (9:00 to 10:30) Open

Apr 16 (9:00 to 10:30) Sharif on new CamKinase results


Apr 24 WEDNESDAY (9:00 to 10:30) CANCELLED

Apr 30 (9:00 to 10:30) CANCELLED

May 7 (9:00 to 10:30) Valery's new extps

May 14 (9:00 to 10:30) Open

May 21 (9:00 to 10:30) CANCELLED

June 11 (9:00 to 10:30) CANCELLED because of Sleep Meeting

June 18 (9:00 to 10:30) Plans for sleep studies

June 25 (9:00 to 10:30) CANCELLED & papers moved to July 9-- expts went too late

July 2 (9:00 to 10:30) Two papers on oreintation plasticity (Shoshana will copy):
Godde, B., Leonhardt, R., Cords, S.M., and Dinse, H.R. (2002) Plasticity of orientation preference maps in the visual cortex of adult cats. Proc Natl Acad Sci U S A 99: 6352-7

Sengpiel, F., Stawinski, P., and Bonhoeffer, T. (1999) Influence of experience on orientation maps in cat visual cortex. Nat Neurosci 2: 727-32

July 9 (9:00 to 10:30) CANCELLED -- Stryker will be away

July 16 (9:00 to 10:30) Patrick goes a chipping ...

July 23 (9:00 to 10:30) CANCELLED -- Because of conflicting experiments.

July 30 (9:00 to 10:30) The first of two papers on V4 receptive fields (Shoshana has copied them for you): Pasupathy, A., and Connor, C.E. (1999) Responses to contour features in macaque area v4. J Neurophysiol 82: 2490-502

August 6 (9:00 to 10:30) The EH&S people will give us our yearly update on saftety and regulatory issues. ALL LAB MEMBERS MUST ATTEND! Barbara Chapman and one of her students will also join us.

August 13 (9:00 to 10:30) The second of two papers on V4 receptive fields (Shoshana has copied them for you): Pasupathy, A., and Connor, C.E. (2001) Shape representation in area v4: Position-specific tuning for boundary conformation. J Neurophysiol 86: 2505-19

August 20 (9:00 to 10:30) CANCELLED -- Stryker will be away

No more lab meetings until September 17

Sep 17 (9:00 to 10:30) We will all discuss progress on current studies (1/2 hour each), so as to acquaint Siegrid with current lab activities

September 19 THURSDAY 12:00 to 1:00 Seminar by Bettina Seri of the Rockefeller, "Radial astrocytes as primary progenitors in the adult dentate gyrus"

October 4 (HSE-810, 9:00 to 10:30) We will ask Siegrid to present some of her recent work

October 11 (Tea room, 9:00 to 10:30) Papers

October 18 (Tea room, 9:00 to 10:30) laila will present two papers:
PS Hyde and EI Knudsen. (Jan 3, 2002) The Optic Tectum Controls Visually Guided Adaptive Plasticity in the Owl's Auditory Space Map. Nature. 415:73-76
Y Gutfreund, W Zheng, EI Knudsen. (Aug 30, 2002) Gated Visual Input to the Central Auditory System. Science. 297: 1556-1558.

October 25 (HSE-810, 9:00 to 10:30) Sunil Ghandi (Salk, UCSD) informal seminar "Kinetics and permeation of single vesicle fusion pores in hippocampal synapses" and visit

November 1 (?, 9:00 to 10:30) We will all bring suggested highlights from the Neuroscience abstracts. one paper BA Linkenhoker and EI Knudsen. (Sept 19, 2002) Incremental Training Increases the Plasticity of the Auditory Space Map in Adult Barn Owls. Nature. 419: 293-296

November 8 (9:00 to 10:30) CANCELLED (Neuroscience Meeting)

November 15 (?, 9:00 to 10:30) Masaaki Sato (Kyoto University) informal seminar "Signaling mechanisms for activity-dependent regulation of Homer 1 immediate early gene"

November 22 (?, 9:00 to 10:30) Jianhua Cang (UCSD) informal seminar "Sensory modification of leech swimming" and "In vivo whole-cell recording of odor-evoked synaptic transmission in rat olfactory bulb"

November 29 (9:00 to 10:30) CANCELLED (Thanksgiving)

December 6 (9:00 to 10:30) Josh Trachtenberg's new manuscript, copy in \\mps-pc23\distribution\inVivoSynapses.pdf

December 10 (9:00 to 10:30 IN HSE-810 Keck Conference room, in place of Dec 13 meeting) Valery will present "Synaptic integration by V1 Neurons depends on location within the orientation map" by Summers, Marino, & Sur (2002) Neuron 36:969-978

Steve Zucker will be visiting from Yale December 17-19, and will give and INFORMAL SEMINAR "Modeling Long-Range Horizontal Interactions in V1" 4:00 PM on Tuesday, December 17, in the Keck Conference room (HSE-810)

December 20 and 27 CANCELLED (Christmas Holiday)

December 17 (TUESDAY, 4 PM, HSE-810) Informal seminar by Steve Zucker

December 20 and 27 CANCELLED (Christmas Holiday)


Jianhua Cang will be arriving in to join the lab on January 15

Dr Megumi Kaneko will visit on Friday, January 17

January 7 (TUESDAY, 9:00 AM, HSW-701) Valery will present Das & Gilbert (1999) Topography of contextual modulations mediated by short-range interactions in primary visual cortex. Nature 399 : 658-661 and Stettler, Das, Bennett & Gilbert (2002) Lateral Connectivity and Contextual Interactions in Macaque Primary Visual Cortex. Neuron 36 : 739-750

January 17 (FRIDAY, 9:00 AM, HSW-701) Informal Seminar by Dr. Megumi Kaneko on Eph/Ephrin Signaling in Axon Sorting in Insect Development

January 24 (FRIDAY, 9:00 AM, HSW-701) We will finish Das & Gilbert (1999) Topography of contextual modulations mediated by short-range interactions in primary visual cortex. Nature 399 : 658-661 and also do Stettler, Das, Bennett & Gilbert (2002) Lateral Connectivity and Contextual Interactions in Macaque Primary Visual Cortex. Neuron 36 : 739-750

January 28 (TUESDAY, 9:00 AM, S-779) We will finish Stettler, Das, Bennett & Gilbert (2002) Lateral Connectivity and Contextual Interactions in Macaque Primary Visual Cortex. Neuron 36 : 739-750

February 4 (TUESDAY, 9:00 AM, S-779) A new paper on sleep Ribeiro, Mello, Velho, Gardner, Jarvis, and Pavlides (2002) Induction of Hippocampal Long-Term Potentiation during Waking Leads to Increased Extrahippocampal zif-268 Expression during Ensuing Rapid-Eye-Movement Sleep Journal of Neuroscience, December 15, 2002, 22(24):10914-10923

February 11 (TUESDAY, 9:00 AM, S-779) Canceled

February 18 (TUESDAY, 9:00 AM, S-779) Will probably be canceled

February 25 (TUESDAY, 9:00 AM, S-779) Mouse experiment plans. Stryker will present for all to discuss and select.

March 4 (TUESDAY, 11:00 AM, HSE-810) Patrick will present Ma et al. (2002) Neurotrophin-3 Is Required for Appropriate Establishment of Thalamocortical Connections. Neuron 36:623 (click here to download)

March 11 (TUESDAY, 9:00 AM, S-779) Open.

March 18 (TUESDAY, 9:00 AM, S-1454) Jaime F. Olavarria University of Washington, Seattle will give an informal seminar RETINAL INFLUENCES ON THE TOPOGRAPHY OF CORTICO-CORTICAL MAPS in S-1454

March 25 (TUESDAY, 9:00 AM, S-779) CANCELLED. Stryker will be away.

April 15 (TUESDAY, 9:00 AM) CANCELLED -- Stryker away.

April 22 (TUESDAY, 9:00 AM, HSW-701) Someone will present Features of Neuronal Synchrony in Mouse Visual Cortex Gabriele Nase, Wolf Singer, Hannah Monyer and Andreas K. Engel and

April 29 (TUESDAY, 9:00 AM) CANCELLED -- Stryker away.

May 6 (TUESDAY, 9:00 AM, HSW-701) We will discuss ocular dominance computations in the mouse and cat.

May 13 (TUESDAY, 9:00 AM, HSW-701) Bosiljka Tasic (Maniatis lab, Harvard) visit and talk on Expression Mechanisms of Clustered Protocadherin Genes.

May 20 (TUESDAY, 9:00 AM, HSW-701) Chapman paper.

May 27 (TUESDAY, 9:00 AM, HSW-701) Paper presentation.

June 10 (TUESDAY, 9:00 AM, HSW-701) Two new methods papers: (1) Figure–ground activity in primary visual cortex (V1) of the monkey matches the speed of behavioral response. Hans Super, Henk Spekreijse, Victor A.F. Lamme, (2003) Neurosci Lett 344:75-78 and (2) Simultaneous mapping of binocular and monocular receptive fields in awake monkeys for calibrating eye alignment in a dichoptical setup. Alexander Gail , Hans Joerg Brinksmeyer, Reinhard Eckhorn (2003) J Neurosci Meth 126:41-56

June 17 (TUESDAY, 9:00 AM, HSW-701) CANCELLED. Stryker will be speaking at the Stanford Photonics Symposium that day. Lab members are welcome to come and ride down with me, although I will not be driving back until after a dinner with the other speakers.

June 24 (TUESDAY, 9:00 AM, HSW-701) Lab meeting moved to WEDNESDAY, June 25, 9:00-10:30 in HSW-701. Sunil will lead discussion of the new paper from Mark Bear's lab Sawtell et al (2003) NMDA Receptor-Dependent Ocular Dominance Plasticity in Adult Visual Cortex, in Neuron, Vol. 38, 977–985, June 19, 2003 .

July 1 (TUESDAY, 9:00-10:00 AM, HSW-701) Each person in the lab will please give a 10-minute summary of progress and plans. Our new lab member, Megumi Kaneko, has arrived and will be there.

July 8(TUESDAY, 9:00-10:00 AM, HSW-701) Open

July 15 (TUESDAY, 9:00-10:30 AM, HSW-701) Edward S. Ruthazer, Colin J. Akerman, Hollis T. Cline (2003) Control of Axon Branch Dynamics by Correlated Activity in Vivo Science 301:66-70

July 22 (TUESDAY, 9:00-10:00 AM, HSW-701) Open

July 29 (TUESDAY, 9:00-10:00 AM, HSW-701) Role of Subplate Neurons in Functional Maturation of Visual Cortical Columns Patrick O. Kanold, Prakash Kara, R. Clay Reid, Carla J. Shatz Science 301:521-525

August 5 (TUESDAY, 9:00-10:00 AM, HSW-701).Heynen et al. (2003) Molecular mechanism of loss of visual cortical responsiveness following brief monocular deprivation. Nature Neurosci 6 : 857-862

August 12 (TUESDAY, 9:00-10:00 AM, HSW-701) Cancelled -- Stryker away

August 19 (TUESDAY, 9:00-10:00 AM, HSW-701) Hilde A. E. Lechner, Edward S. Lein, and Edward M. Callaway (2002) A Genetic Method for Selective and Quickly Reversible Silencing of Mammalian Neurons. Journal of Neuroscience,22 : 5287–5290

August 26 (TUESDAY, 9:00-10:00 AM, HSW-701) Cancelled -- Stryker away

September 2 (TUESDAY, 9:00-10:00 AM, HSW-701) Cancelled -- Stryker away

September 9 (TUESDAY, 9:00-10:00 AM, HSW-701). Basole A, White LE, Fitzpatrick D. (2003) Mapping multiple features in the population response of visual cortex. Nature 423, 986 - 990

September 16 Cancelled -- Neuroscience Asilomar meeting

September 23 (TUESDAY, 9:00-10:00 AM, HSW-701). A discussion with Jaime Olavarria of the new experiments he is working on with our lab.

September 30 Cancelled -- Stryker away

October 7 (TUESDAY, 9:00-10:00 AM, HSW-701). Two papers: Val will present Liu GB, Zhang Y, Pettigrew JD, Xu WF, Li CY. (2003) Spreading and synchronization of intrinsic signals in visual cortex of macaque monkey evoked by a localized visual stimulus. Brain Res.985:13-20. and Sunil will present Villeneuve MY, Casanova C (2003) On the use of isoflurane versus halothane in the study of visual response properties of single cells in the primary visual cortex. J Neurosci Methods. 29:19-31.

October 14 (TUESDAY, 9:00-10:30 AM, HSW-701). A paper from Jeff Lichtman. I suggest that Megumi present it: Kasthuri, N., and Lichtman, J.W. (2003) The role of neuronal identity in synaptic competition. Nature 424: 426-30

October 21 (TUESDAY, 9:00-10:30 AM, HSW-701).The second paper of the pair begun on October 14, to be presented by Matt Caywood: Buffelli, M., Burgess, R.W., Feng, G., Lobe, C.G., Lichtman, J.W., and Sanes, J.R. (2003) Genetic evidence that relative synaptic efficacy biases the outcome of synaptic competition. Nature 424: 430-4

October 28 Cancelled -- Stryker away

November 4 (TUESDAY, 9:00-10:30 AM, HSW-701). Another new paper about turnover of synapses, to be presented by Sunil: Gan, W.B., Kwon, E., Feng, G., Sanes, J.R., and Lichtman, J.W. (2003) Synaptic dynamism measured over minutes to months: Age-dependent decline in an autonomic ganglion. Nat Neurosci 6: 956-960

Novemer 11 Cancelled -- Neuroscience Meeting

November 18 (TUESDAY, 9:00-10:30 AM, HSW-701). Bring your summary of the most interesting neuroscience presenations.

November 25 (TUESDAY, 9:00-10:30 AM, HSW-701). More Neuroscience meeting highlights: Laila, Valery, perhaps others

December 2 (TUESDAY, 9:00-10:30 AM, HSW-701). A new Grinvald lab paper on spontaneous cortical states, finally with an analysis that does not depend on spike triggered averaging. I will suggest Yuri present it. Tal Kenet, Dmitri Bibitchkov, Misha Tsodyks, Amiram Grinvald & Amos Arieli (2003) Spontaneously emerging cortical representations of visual attributes. NATURE 425: 954-956 Also see Supplementary material

December 9 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Continuing on the papers above, analyzing whether the Kohonen procedure gets the most information from the VSD datasets, and what the implications of these maps are for cortical circuitry and inputs.

December 16 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Talk by Andrew Huberman from Barbara Chapman's lab: "Activity and axon guidance cue regulation of eye-specific segregation"

December 23 Cancelled -- Holiday

December 30 Cancelled -- Holiday


January 6 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Jianhua will present two Neuron papers on AChR function: (1) Todd McLaughlin, Christine L. Torborg, Marla B. Feller and Dennis D.M. O'Leary (2003) Retinotopic Map Refinement Requires Spontaneous Retinal Waves during a Brief Critical Period of Development , Neuron 40:1147 , (2) Matthew S. Grubb, Francesco M. Rossi, Jean-Pierre Changeux, and Ian D. Thompson (2003) Abnormal Functional Organization in the Dorsal Lateral Geniculate Nucleus of Mice Lacking the ?2 Subunit of the Nicotinic Acetylcholine Receptor Neuron 40:1161

January 13 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Cancelled -- Stryker away

January 20 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Open, possibly to be held early or late so that we can attend Ben Cravatt Seminar

January 27 (TUESDAY, 12:00 - 1:30 PM, HSE-810). A new paper on temporal lobe visual cortex: Tsao et al (2003) Faces and objects in macaque cerebral cortex Nature Neurosci 6:989-995

February 3 (TUESDAY, 12:00 - 1:30 PM, HSE-810). New O'Leary paper

February 10 (TUESDAY, 12:00 - 1:30 PM, HSE-810). A paper from the Ramoa lab using visual cortical plasticity to examine pathology of fetal alcohol syndrome: J Neurosci. 2003 Nov 5; 23(31): 10002-12. Neonatal alcohol exposure induces long-lasting impairment of visual cortical plasticity in ferrets. Medina AE, Krahe TE, Coppola DM, Ramoa AS

February 17 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Cancelled -- Stryker away until afternoon

May 4 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Jianhua Cang will tell us the highlights of the mouse vision pre-meeting at ARVO and of any ARVO highlights.

May 11 (TUESDAY, 12:00 - 1:30 PM, HSE-810).Cris Niell from Steve Smith's lab at Stanford will be visiting the lab on Tuesday and will give an informal talk at lab meeting on "Imaging structural and functional development of the zebrafish visual system"

May 18 (TUESDAY, 12:00 - 1:30 PM, HSE-810).

May 25 (TUESDAY, 12:00 - 1:30 PM, HSE-810). A new paper from the Sakmann lab, for Sunil to present: Petersen CC, Brecht M, Hahn TT, Sakmann B. (2004) Synaptic changes in layer 2/3 underlying map plasticity of developing barrel cortex. Science. 304:739-42 and, if he has time, a second really neat finding: Brecht M, Schneider M, Sakmann B, Margrie TW. (2004) Whisker movements evoked by stimulation of single pyramidal cells in rat motor cortex. Nature 427:704-10. Papers names are links for downloading.

June 1 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Megumi will lead us on discussion of two papers about the barrel circuit and plasticity Shepherd GM, Pologruto TA, Svoboda K. (2003) Circuit analysis of experience-dependent plasticity in the developing rat barrel cortex. Neuron. 38:277-89. and Wallace H, Fox K. (1999) Local cortical interactions determine the form of cortical plasticity. J Neurobiol. 41:58-63

June 8 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Jianhua will lead us on discussion of a recent paper from the Axel lab. Yu et al (2004) Spontaneous Neural Activity Is Required for the Establishment and Maintenance of the Olfactory Sensory Map. Neuron 42: 553-566

June 15 (TUESDAY, 12:00 - 1:30 PM, HSE-810).Laila will lead us on discussion of a recent paper from the Ramoa lab Liao DS, Krahe TE, Prusky GT, Medina AE, Ramoa AS. Recovery of Cortical Binocularity and Orientation Selectivity after the Critical Period for Ocular Dominance Plasticity. J Neurophysiol. 2004 Apr 21 [Epub ahead of print], which draws heavily on a background paper Liao DS, Mower AF, Neve RL, Sato-Bigbee C, Ramoa AS. Different mechanisms for loss and recovery of binocularity in the visual cortex. J Neurosci. 2002 Oct 15;22(20):9015-23..

June 22 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Let us read the following new paper. I will ask someone to present it. . Masanori Matsuzaki, Naoki Honkura, Graham C. R. Ellis-Davies & Haruo Kasai (2004) Structural basis of long-term potentiation in single dendritic spines Nature 429:761-766 (June 17 issue) Supplementary information

July 6 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Let us read the following new paper on barrels. who would like to present? Please let the rest of the lab know. Ingrid Bureau, Gordon M.G. Shepherd, and Karel Svoboda* (2004) Open Precise Development of Functional and Anatomical Columns in the Neocortex. Neuron. 42:789–801 (June 10 issue)

July 13 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Let us read and discuss the following paper from Yang Dan's lab . Haishan Yao, Yaosong Shen and Yang Dan (2004) Intracortical mechanism of stimulus-timing-dependent plasticity in visual cortical orientation tuning. PNAS 101:5081-5086 Any volunteers to present it?

July 20 Cancelled--Stryker away

July 27 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Let us go around and have brief progress reports from everybody.

August 3 Cancelled--Stryker away

August 10 Cancelled--Stryker away

August 17 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Misha Tsodyks, a theorist from the Weizmann Institute in Israel will be visiting the Miller lab and will give a talk on "Spontaneous population activity in primary visual cortex" . On Wednesday noon, will give a second, very informal chalk talk on some other topics he's working on, e.g. associative memory models and perceptual learning

August 24 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Kevin Fox from Cardiff, Wales, will visit and give an informal seminar on his work on the barrel cortex.

August 31 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Lalia will present the following new paper on sleep . Reto Huber, M. Felice Ghilardi, Marcello Massimini & Giulio Tononi (2004) Local sleep and learning NATURE 430: 78-81 along with News and Views Nature 430: 27 - 28 Neurobiology: Sleep on it by Ilana S. Hairston and Robert T Knight

September 7 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Laila will review her research progress.

September 14 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Michael Silver (Heeger lab, Stanford, and D'Esposito lab, Berkeley) will give an informal talk on his human studies on spatial attention: "Human visual spatial attention: topographic maps, top-down processing, and cholinergic modulation"

September 21 -- Cancelled because of Neuroscience Asilomar meeting

September 28 (TUESDAY, 12:00 - 1:30 PM, HSE-810). Xiaorong Liu from the Copenhagen lab will discuss with us their new work on TrkB signaling in the retina

October 19 (Tuesday, 12:00 to 1:00) We will have a brief Lab Meeting to discuss a lab helper for the mice, to discuss forthcoming highlights of the Neuroscience meeting, to answer a few quations about our own abstracts, and to hear about a few highlights from the Jackson Lab mouse vision workshop.

November 2 (Tuesday, 12:00 to 1:30) Bring your highlights of the neuroscience Meeitng to present

November 9 (Tuesday, 12:00 to 1:30) Cancelled--Stryker Away

November 16 (Tuesday, 12:00 to 1:30) Sunil and JC will present Lu W, Constantine-Paton M. (2004) Eye opening rapidly induces synaptic potentiation and refinement. Neuron 43:237-49.

Maffei A, Nelson S, Turrigiano G. (2004) Selective reconfiguration of layer 4 visual cortical circuitry by visual deprivation. Nat Neurosci.

November 23 (Tuesday, 12:00 to 1:30) We will discuss a new paper about binocular vision from the O'Leary and Pfaff labs. Sorry for the late notice. Winnie Pak, Robert Hindges, Yoo-Shick Lim, Samuel L. Pfaff and Dennis D. M. O'Leary (2004) Magnitude of Binocular Vision Controlled by Islet-2 Repression of a Genetic Program that Specifies Laterality of Retinal Axon Pathfinding. Cell 119 : 567-578, Issue 4 , 12 November 2004

November 30 (Tuesday, 12:00 to 1:00) JC will present work on the analysis of segregated retrograde projections.

December 7 (Tuesday, 12:00 to 1:30) Todd Anthony from the nat Heinz lab at the Rockefeller will visit and give an informal seminar on his Ph.D. work on "Radial Glial Cells: Roles as Neural Progenitors and Pathways Regulating their Function"

December 14 (Tuesday, 12:00 to 1:30) Megumi will lead a discussion about some new papers on CREB from Tony Pham:
SEIGO SUZUKI,SALWA AL-NOORI, SHEHZAD A. BUTT, AND TONY A. PHAM (2004) Regulation of the CREB Signaling Cascade in the Visual Cortex by Visual Experience and Neuronal Activity. J Comp Neur 479:70-83.

December 21 (Tuesday, 12:30 to 1:30) NOTE-- MEETING 1/2 hour later than usual. Megumi will lead a discussion about some new papers on CREB from Tony Pham:
Tony A. Pham, Sarah J. Graham, Seigo Suzuki, Angel Barco,Eric R. Kandel, Barbara Gordon, and Marvin E. Lickey (2004) A semi-persistent adult ocular dominance plasticity in visual cortex is stabilized by activated CREB. Learning and Memory


December 28 (Tuesday, 12:00 to 1:30) Cancelled -- Christmas Holiday


January 4 (Tuesday, 2:00 to 3:00) Schedule next few meetings

January 13 (Thursday, 1:00 to 3:00) Matt Caywood on a new paper from Alex Pouget on orientation tuning Series P, Latham PE, Pouget A (2004) Tuning curve sharpening for orientation selectivity: coding efficiency and the impact of correlations. Nat Neurosci 7:1129-1135. (For background also see earlier papers: Deneve S, Latham PE, Pouget A (1999) Reading population codes: a neural implementation of ideal observers. Nat Neurosci 2:740-745. and Deneve S, Latham PE, Pouget A (2001) Efficient computation and cue integration with noisy population codes. Nat Neurosci 4:826-831.)

January 20 (Thursday, 1:00 to 3:00) Patrick McQuillen on new technology an memory consolidation, a paper from Joe Tsien's lab: Cui Z, Wang H, Tan Y, Zaia KA, Zhang S, Tsien JZ (2004) Inducible and reversible NR1 knockout reveals crucial role of the NMDA receptor in preserving remote memories in the brain. Neuron 41:781-793. (some background in Wang H, Shimizu E, Tang YP, Cho M, Kyin M, Zuo W, Robinson DA, Alaimo PJ, Zhang C, Morimoto H, Zhuo M, Feng R, Shokat KM, Tsien JZ (2003) Inducible protein knockout reveals temporal requirement of CaMKII reactivation for memory consolidation in the brain. Proc Natl Acad Sci U S A 100:4287-4292.)

January 25 (Tuesday, 12:00 to 1:30) Ling on the refinement of inhibitory connections, from karl Kandler's lab: Kandler K (2004) Activity-dependent organization of inhibitory circuits: lessons from the auditory system. Curr Opin Neurobiol 14:96-104.and Kim G, Kandler K (2003) Elimination and strengthening of glycinergic/GABAergic connections during tonotopic map formation. Nat Neurosci 6:282-290.

February 1 (Tuesday, 12:00 to 1:30) Sunil on analysis of cortical circuitry by multi-site optical recording in vitro and electrical recordings in vivo, papers from Rafa Yuste's lab: Cossart R, Aronov D, Yuste R (2003) Attractor dynamics of network UP states in the neocortex. Nature 423:283-288. and Ikegaya Y, Aaron G, Cossart R, Aronov D, Lampl I, Ferster D, Yuste R (2004) Synfire chains and cortical songs: temporal modules of cortical activity. Science 304:559-564.

February 8 (Tuesday, 12:00 to 1:30) Jianhua progress report

February 15 (Tuesday, 12:00 to 1:30) Cancelled -- Stryker away

February 22 (Tuesday, 12:00 to 1:30) Cancelled -- Stryker away

March 1 (Tuesday, 12:00 to 1:30) Glen Prusky will give an informal seminar on "Experience-Dependent Plasticity of Cortical Motion Vision" and will visit with the lab.

March 8 (Tuesday, 12:00 to 1:30) Tatyana Sharpee progress report.

March 15 (Tuesday, 12:00 to 1:30) Masaaki Sato will present a paper on synapse formation: Ethan R. Graf, XueZhao Zhang, Shan-Xue Jin, Michael W. Linhoff, and Ann Marie Craig (2004) Neurexins Induce Differentiation of GABA and Glutamate Postsynaptic Specializations via Neuroligins. Cell 119:1013-1026

March 22 (Tuesday, 12:00 to 1:30) We will all discuss a new paper on corticla networks: Yumiko Yoshimura, Jami L. M. Dantzker & Edward M. Callaway (2005) Excitatory cortical neurons form fine-scale functional networks. Nature 433: 868-875 (local copy here)

RESCHEDULED TO 2:00-3:30 in HSW-701 March 29 (Tuesday, 12:00 to 1:30) We will all discuss another new paper on cortical networks: Kenichi Ohki, Sooyoung Chung, Yeang H. Ch’ng, Prakash Kara & R. Clay Reid (2005) Functional imaging with cellular resolution reveals precise microarchitecture in visual cortex. Nature 433: 597-603 (local copy here)

Exceptional Day April 6 (Wednesday, 10:00 - 11:30, in HSW-701) Tatyana will lead discussion of Luis M Martinez, Qingbo Wang, R Clay Reid, Cinthi Pillai, José-Mañuel Alonso, Friedrich T Sommer & Judith A Hirsch (2005) Receptive field structure varies with layer in the primary visual cortex. Nature Neuroscience 8: 372 - 379 (local copy here , News & Views here)

April 12 (Tuesday, 10:00 - 11:30, in HSW-701) A new STDP slice paper: Robert C. Froemke, Mu-ming Poo & Yang Dan (2005) Spike-timing-dependent synaptic plasticity depends on dendritic location. Nature 434: 221-225

April 19 (Tuesday, 10:00 - 11:30, in HSW-701) This and the next week are two papers on the interpretation of imaging findings from cat visual cortex: Tanya I. Baker and Naoum P. Issa (2005) Cortical maps of separable tuning properties predict population responses to complex visual stimuli. J Neurophysiol epub doi:10.1152/jn.01093.2004

April 26 (Tuesday, 10:00 - 11:30, in HSW-701) Valerio Mante and Matteo Carandini (2005) Mapping of stimulus energy in primary visual cortex. J Neurophysiol epub doi:10.1152/jn.01094.2004

May 3 (Tuesday, 10:00 - 11:30, in HSW-701) Cancelled--Stryker away

May 10 (Tuesday, 10:00 - 11:30, in HSW-701) JC will present a very clever new mapping finding and a model: Reber M, Burrola P, Lemke G. (2004) A relative signalling model for the formation of a topographic neural map. Nature. 431:847-53 with supplement

May 17 (Tuesday, 10:00 - 11:30, in HSW-701) Tatyana suggested a new paper on the development of a higher cortical area Bin Zhang, Jianghe Zheng, Ichiro Watanabe, Ichiro Maruko, Hua Bi, Earl L. Smith III, and Yuzo Chino (2005) Delayed maturation of receptive field centersurround mechanisms in V2 PNAS 102: 5862–5867

May 24 (Tuesday, 10:00 - 11:30, in HSW-701) Masaaki will lead discussion of Yupeng Yang, Quentin S Fischer, Ying Zhang, Karsten Baumgärtel, Isabelle M Mansuy & Nigel W Daw (2005) Reversible blockade of experience-dependent plasticity by calcineurin in mouse visual cortex. Nature Neuroscience Published online: 8 May 2005; | doi:10.1038/nn1464 and Supplement

May 31 (Tuesday, 10:00 - 11:30, in HSW-701) Sunil will lead discussion of transplantation project proposal

June 7 (Tuesday, 10:00 - 11:30, in HSW-701) Cris will lead discussion of Hua JY, Smear MC, Baier H, Smith SJ. (2005) Regulation of axon growth in vivo by activity-based competition. Nature. 434:1022-1026.

June 14 (Tuesday, 10:00 - 11:30, in HSE-810) Matt Caywood will give a progress report.

June 21 (Tuesday, 10:00 - 11:30, in HSE-810) First half-hour (10:00-10:30): Thomas Lee from Stanford will visit and give an informal talk about imaging technologies. Next hour (10:30 - 11:30 or so): Andrei Kurgansky will give a progress report.

June 28 (Tuesday, 10:00 - 11:30, in HSE-810) Ling will present a new intracellular analysis of simple cell receptive fields: Nicholas J. Priebe and David Ferster (2005) Direction Selectivity of Excitation and Inhibition in Simple Cells of the Cat Primary Visual Cortex. Neuron, 45: 133–145

July 5 (Tuesday, 10:00 - 11:30, in HSW-701) Matt Caywood will lead discussion of new results on cross-orientation inhibition (unpublished and still confidential, on lab-specific page): Nicholas J Priebe & David Ferster (2005) Mechanisms underlying cross-orientation suppression in cat visual cortex. Supplementary Data

July 12 (Tuesday, 10:00 - 11:30, in HSE-810) Tatyana will present Rust NC, Schwartz O, Movshon JA, Simoncelli EP Spatiotemporal elements of macaque v1 receptive fields. Neuron. 2005 Jun 16;46(6):945-56. Supplement

July 19 (Tuesday, 10:00 - 11:30, in HSE-810) Cris will present the set of papers on the cortical representation of figure and ground: Overview by Ken Nakayama (2005) Resolving Border Disputes in Midlevel Vision. Neuron.47::5-8
Qiu FT, von der Heydt R. (2005) Figure and ground in the visual cortex: v2 combines stereoscopic cues with gestalt rules. Neuron. 47(1):155-66.

Li Zhaoping (2005) Border Ownership from Intracortical Interactions in Visual Area V2 Neuron 47(1):143-153.

July 26 (Tuesday, 10:00 - 11:30, in HSE-810) Cancelled

August 2 (Tuesday, 10:00 - 11:30, in HSE-810) Brendan will present Olshausen BA, Field DJ. How close are we to understanding V1? Neural Comput. 2005 Aug;17(8):1665-99.

August 9 (Tuesday, 10:00 - 11:30, in HSE-810) Melinda will present Yi Zuo, Guang Yang, Elaine Kwon & Wen-Biao Gan (2005) Long-term sensory deprivation prevents dendritic spine loss in primary somatosensory cortex Nature 436:261-265.

August 16 (Tuesday, 10:00 - 11:30, in HSE-810) Cancelled--vacation

August 23 (Tuesday, 10:00 - 11:30, in HSE-810) Cancelled--vacation

August 30 Cancelled--too many people still away

September 6 Cancelled--Stryker away

September 13 (Tuesday, 10:00 - 11:30, in HSE-810) Jianhua will present Song S, Sjostrom PJ, Reigl M, Nelson S, Chklovskii DB. Highly nonrandom features of synaptic connectivity in local cortical circuits. PLoS Biol. 2005 Mar;3(3):e68. Epub 2005 Mar 1.

September 20 (Tuesday, 10:00 - 11:30, in HSE-810) Ling will discuss Sengpiel F, Vorobyov V. Intracortical origins of interocular suppression in the visual cortex. J Neurosci. 2005 Jul 6;25(27):6394-400 as well as her Woods Hole project. Laila will show the results of some of her analyses. Goodbye lunch for Cheila immediately afterward.

September 27 Cancelled--Neuroscience Asilomar

October 4 (Tuesday, 10:00 - 11:30, in HSE-810) Melinda will present Aaron W. McGee, Yupeng Yang, Quentin S. Fischer, Nigel W. Daw, and Stephen M. Strittmatter (2005) Experience-Driven Plasticity of Visual Cortex Limited by Myelin and Nogo Receptor. Science 309: 2222-2226. (30 September 2005) [PDF] [Supporting Online Material]

October 11 (Tuesday, 10:00 - 11:30, in HSE-810) Could someone please volunteer to present Yoshiaki Tagawa, Patrick O Kanold, Marta Majdan & Carla J Shatz (2005) Multiple periods of functional ocular dominance plasticity in mouse visual cortex NATURE NEUROSCIENCE 8:380-388 ?

October 18 (Tuesday, 10:00 - 11:30, in HSE-810) Plans and progress from Cris

October 25 (Tuesday, 10:00 - 11:30, in HSE-810) Progress report from Patrick

November 1 (Tuesday, 10:00 - 11:30, in HSE-810) Cancelled because of IACUC Meeting

November 8 (Tuesday, 10:00 - 11:30, in HSE-810) Neuroscience Meeting Preview. Please bring a list of events you would like to make sure are covered by someone in the lab.

November 15 (Tuesday, 10:00 - 11:30, in HSE-810) Cancelled because of Neuroscience meeting in Washington

November 22 (Tuesday, 10:00 - 11:30, in HSE-810) Neuroscience Post Meet'um Post Mortem

November 29 (Tuesday, 10:00 - 11:30, in HSE-810) Matt Caywood will present Kerr, JND, Greenberg, D, Helmchen F (2005) Imaging input and output of neocortical networks in vivo. ; 11:00-11:30 for Emergency Response Awareness and Hazard Communication Training Session (all lab members are required to attend this).

December 6 (Tuesday, 10:00 - 11:30, in HSE-810) More on plasticity strategies and traces. Everyone should try to look at these--some intersting commonalities.:

December 13 (Tuesday, 10:00 - 11:30, in HSE-810) Bring your proposed circuits to account for critical period and adult plasticity. We will look at the alternatives and discuss how to test them.

December 20, 27, and January 3 Cancelled, Christmas Holiday and Travel


January 10 (Tuesday, 10:00 - 11:30, in HSE-810) Second Round: Bring your proposed circuits to account for critical period and adult plasticity IN WRITTEN FORM, and summarize the plasticity rules for each kind of connection and the critical points that might be tested. See Matt's email about the Wiki for summaries of data.

January 17 (Tuesday, 10:00 - 11:30, in HSE-810) Two neat new papers on visual cortex. If no one volunteers, we can just go over them together in lab meeting.

January 24 (Tuesday, 10:00 - 11:30, in HSE-810) A new paper on neuronal identity: Sugino K, Hempel CM, Miller MN, Hattox AM, Shapiro P, Wu C, Huang ZJ, Nelson SB. Molecular taxonomy of major neuronal classes in the adult mouse forebrain. Nat Neurosci. 2006 Jan;9(1):99-107 article supplement news&views by E. Diazz

January 31 (Tuesday, 10:00 - 11:30, in HSE-810) Another new paper on neuronal identity:. Butt SJ, Fuccillo M, Nery S, Noctor S, Kriegstein A, Corbin JG, Fishell G. The temporal and spatial origins of cortical interneurons predict their physiological subtype. Neuron. 2005 Nov 23;48(4):591-604. article supplement preview by R Yuste

February 7 (Tuesday, 10:00 - 11:30, in HSE-810)Canceled--Stryker away

February 14 Canceled--Site Visit

February 21(Tuesday, 10:00 - 11:30, in HSE-810)Canceled--Winter Holiday

February 28(Tuesday, 10:00 - 11:30, in HSE-810) Patrick will present Dupont E, Hanganu IL, Kilb W, Hirsch S, Luhmann HJ. Rapid developmental switch in the mechanisms driving early cortical columnar networks. Nature. 2006 Jan 5;439(7072):79-83. Epub 2005 Dec 4

March 14 (Tuesday, 10:00 - 11:30, in HSE-810)JC will present new paper for Ghosh lab, and Cris will review highlights of this week's CSHL meeting: Gulayse Ince-Dunn, Benjamin J. Hall, Shu-Ching Hu, Beth Ripley, Richard L. Huganir, James M. Olson, Stephen J. Tapscott and Anirvan Ghosh (2006) Regulation of Thalamocortical Patterning and Synaptic Maturation by NeuroD2 . Neuron, Vol 49, 683-695, 02 March 2006

March 21 (Tuesday, 10:00 - 11:30, in HSE-810)Megumi will present her progress report.

March 28 (Tuesday, 10:00 - 11:30, in HSE-810)Canceled--Stryker away

April 4 (Tuesday, 10:00 - 11:30, in HSE-810)Melinda will present 2 of the following papers 4 new papers the Yuste lab and

April 11 (Tuesday, 10:00 - 11:30, in HSE-810)We will decide later. Volunteers?

April 18 (Tuesday, 10:00 - 11:30, in HSE-810)Canceled--Stryker away

May 2 (Tuesday, 10:00 - 11:30, in HSE-810) Melinda will present a paper on plasticity in adult rats after 10 days in the dark: He et al., Visual deprivation reactivates rapid ocular dominance plasticity in adult visual cortex, J Neurosci. 2006 26:2951-5. (

May 9 (Tuesday, 10:00 - 11:30, in HSE-810) A brief meeting of mouse users to talk about hosuing and some technology issues

May 16 (Tuesday, 9:00 - 10:30, in HSE-810) A recent paper on gene expression in developjg visual cortex: NOTE EARLIER TIME FOR THIS ONE MEETING
Majdan M, Shatz CJ. Effects of visual experience on activity-dependent gene regulation in cortex. Nat Neurosci. 2006 May;9(5):650-9.

May 23 (Tuesday, 10:00 - 11:30, in HSE-810) Cancelled--Stryker away

May 30 (Tuesday, 10:00 - 11:30, in HSE-810) SMasaaki will present Tropea D, Kreiman G, Lyckman A, Mukherjee S, Yu H, Horng S, Sur M. Gene expression changes and molecular pathways mediating activity-dependent plasticity in visual cortex. Nat Neurosci. 2006 May;9(5):660-8.

June 6 (Tuesday, 10:00 - 11:30, in HSE-810) Cris will present Isabelle Ferezou, Sonia Bolea and Carl C.H. Petersen Visualizing the Cortical Representation of Whisker Touch: Voltage-Sensitive Dye Imaging in Freely Moving Mice Neuron 50: 617–629 (May 18 issue)

June 13 (Tuesday, 10:00 - 11:30, in HSE-810) Tatyana will present Elad Schneidman, Michael J. Berry, Ronen Segev, William Bialek (2006) Weak pairwise correlations imply strongly correlated network states in a neural population. Nature 440, 1007-1012 (20 Apr 2006)

June 20 (Tuesday, 10:00 - 11:30, in HSE-810) Matt Caywood will present Shuler MG, Bear MF (2006) Reward timing in the primary visual cortex. Science. 2006 Mar 17;311(5767):1606-9. supplement

June 27 (Tuesday, 10:00 - 11:30, in HSE-810) Louis Ptacek will visit and discuss "Does audiogenic epilepsy in the Frings mouse result from a developmental disorder?" Three References: Neuron, Vol. 31, 537–544, 2001 A Novel Gene Causing a Mendelian Audiogenic Mouse Epilepsy Genomics 85 (2005) 582 – 590 The Mass1frings mutation underlies early onset hearing impairment in BUB/BnJ mice, a model for the auditory pathology of Usher syndrome IIC Epilepsy Research 62 (2004) 13–25 c-Fos immunohistochemical mapping of the audiogenic seizure network and tonotopic neuronal hyperexcitability in the inferior colliculus of the Frings mouse

July 4 and July 11-- cancelled

July 18 (Tuesday, 10:00 - 11:30, in HSE-810) Cris will present a new Sakmann lab paper on thalmocortical connectivity: Bruno, R.M & Sakmann, B. (2006) Cortex Is Driven by Weak but Synchronously Active Thalamocortical Synapses SCIENCE 312: 1622-1628.

July 25 Cancelled--Stryker away

August 1 Tuesday, 10:00 - 11:30, in HSE-810) Sharif Taha will present his new work using chronic recording from rats.

August 8 Cancelled--Stryker away

August 15 Tuesday, 10:00 - 11:30, in HSE-810) Melinda will present Mikhail Y. Frenkel, Nathaniel B. Sawtell, Antonia Cinira M. Diogo, Bongjune Yoon, Rachael L. Neve, and Mark F. Bear (2006) Instructive Effect of Visual Experience in Mouse Visual Cortex Neuron 51: 339-349

August 22 Tuesday, 10:00 - 11:00, in HSE-810) short meeting. Please volunteer to present Albert K. Lee, Ian D. Manns, Bert Sakmann, and Michael Brecht (2006)Whole-Cell Recordings in Freely Moving Rats Neuron 51:399-407 On Web in current issue August 17, 2006

August 29 Cancelled

September 5 Cancelled for Holiday Absences

September 12 (Tuesday, 10:00 - 11:30, in HSE-810)

September 19 Cancelled for Asilomar

September 26 (Tuesday, 10:00 - 11:30, in HSE-810) Cancelled

October 3 (Tuesday, 10:00 - 11:30, in HSE-810) Masaaki will present new findings. Discussion on differences between adult and critical period plasticity

October 10 (Tuesday, 10:00 - 11:30, in HSE-810) Megumi will present her new work on TNF-alpha and synaptic scaling.

October 17 Cancelled for Neuroscience meeting

October 24 (Tuesday, 10:00 - 11:30, in HSE-810) Cris and Sunil on derivation of receptive fields from different sorts of data.

October 30 (Monday 12:00 noon - 1:00 PM, in HSE 810) Nadine Gogolla, Friedrich Miescher Institute for Biomedical Research Basel, Switzerland, will visit the lab starting at 10:30 and will give a noon seminar on "Experience-dependent anatomical rearrangements of synaptic connectivity in the adult CNS"

October 31 (Tuesday, 10:00 - 11:30, in HSE-810) Tatyana on predictive power of linear and linear-nonlinear models.

November 7 (Tuesday, 10:00 - 11:30, in HSE-810) Melinda on her new work

November 14 (Tuesday, 10:00 - 11:30, in HSE-810) Cancelled--Stryker away

November 21 (Tuesday, 10:00 - 11:30, in HSE-810) Cancelled.

November 28 (Tuesday, 10:00 - 11:30, in HSE-810) Stryker will present wo new papers from the Shatz lab:
Patrick O. Kanold1 and Carla J. Shatz (2006) Subplate Neurons Regulate Maturation of Cortical Inhibition and Outcome of Ocular Dominance Plasticity Neuron, Vol 51, 627-638.

Josh Syken, Tadzia GrandPre, Patrick O. Kanold, Carla J. Shatz (2006) PirB Restricts Ocular-Dominance Plasticity in Visual Cortex. Science 313: 1795 - 1800

Some other interesting new papers on rodent cortex:

Chakravarthy, S., Saiepour, M. H., Bence, M., Perry, S., Hartman, R., Couey, J. J., Mansvelder, H. D. and Levelt, C. N. (2006) Postsynaptic TrkB signaling has distinct roles in spine maintenance in adult visual cortex and hippocampus. Proc Natl Acad Sci U S A 103: 1071-6.

Nuriya, Jiang, Nemet, Eisenthal & Yuste (2006) Imaging membrane potential in dendritic spines. PNAS 103: 786-790

Dumitriu, D., Cossart, R., Huang, J. and Yuste, R. (2006) Correlation Between Axonal Morphologies and Synaptic Input Kinetics of Interneurons from Mouse Visual Cortex. Cereb Cortex

Pizzorusso T, Medini P, Landi S, Baldini S, Berardi N, Maffei L. (2006) Structural and functional recovery from early monocular deprivation in adult rats. Proc Natl Acad Sci U S A. 2006 May 30;103(22):8517-22. Epub 2006 May 18.

Naundorf B, Wolf F, Volgushev M. (2006) Unique features of action potential initiation in cortical neurons. Nature. 2006 Apr 20;440(7087):1060-3.(also see commentary: Nature. Apr 20;440(7087):999-1000.) ----

Olavarria JF, Safaeian P (2006) Development of callosal topography in visual cortex of normal and enucleated rats. . J Comp Neurol. Jun 1;496(4):495-512.

December 5 (Tuesday, 10:00 - 11:30, in HSE-810) Melinda will present the Arc paper from the Tonegawa and Sur labs: Wang, K. H., Majewska, A., Schummers, J., Farley, B., Hu, C., Sur, M. and Tonegawa, S. (2006) In vivo two-photon imaging reveals a role of arc in enhancing orientation specificity in visual cortex. Cell 126: 389-402. Supplement

December 12 (Tuesday, 10:00 - 11:30, in HSE-810) Continuation of Melinda's presentation of the Arc paper (above, Dec 5)

December 19 Cancelled for Christmas Holiday

December 26 Cancelled for Christmas Holiday


January 2 Cancelled for New Year Holiday

January 9 (Tuesday) Cancelled, too many people are away

January 16 (Tuesday) Cancelled

January 23 (Tuesday, 10:00 - 11:00, in HSE-810) Kurt Ahrens of the Allen Brain Institute in Seattle will be visiting the lab, and he will make a presentation about some of the work and plans there.

January 30 (Tuesday, 10:00 - 11:30, in HSE-810) Open

February 6 (Tuesday) Canceled

February 14 (Wednesday, 10:00-11:30 in HSW-701) Group discussion of Smith SL, Trachtenberg JT. Experience-dependent binocular competition in the visual cortex begins at eye opening. Nat Neurosci. 2007 Feb 11; [Epub ahead of print]

February 21 (Wednesday, 10:00 - 11:00, in HSW-701) Lily Jan will talk with us about Regulation of KV1 potassium channels by neural activity

February 27 (Tuesday) Canceled--Stryker away

March 6 (Tuesday, 10:30-11:30 in HSE-810) Heimel JA, Hartman RJ, Hermans JM, Levelt CN. (2007) Screening mouse vision with intrinsic signal optical imaging. Eur J Neurosci. 25:795-804. (Note late Start for this meeting!)

March 20 (Tuesday, 10:00-11:30 in HSE-810) Masaaki wil present some of his recent work.

March 27 (Tuesday, 10:00-11:30 in HSE-810) Cris will present Ringach DL (2007) On the Origin of the Functional Architecture of the Cortex. PLoS ONE 2(2): e251. doi:10.1371/journal.pone.0000251 You will need also to read some of the essential background for this paper in Ringach, DL (2004) Haphazard wiring of simple receptive fields and orientation columns in visual cortex. J Neurophysiol. 92: 468-76.

April 26 (Thursday, 5:15-6:15 in HSE-810) Lab will meet with Seminar Speaker Dmitri Chklovskii (after his seminar)

May 4 (Friday, 10:00-11:30 in HSW-701) Open.

May 18 (Friday, 10:00-11:30 in HSW-701) Cris will present two new papers on circuit tracing: Wickersham IR, Lyon DC, Barnard RJ, Mori T, Finke S, Conzelmann KK, Young JA, Callaway EM. Monosynaptic restriction of transsynaptic tracing from single, genetically targeted neurons. Neuron. 2007 Mar 1;53(5):639-47. AND Petreanu L, Huber D, Sobczyk A, Svoboda K. Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections. Nat Neurosci. 2007 May;10(5):663-8. .

May 23 (Wednesday, 4:00-5:30 in HSE-810) We will meet to discuss concrete plans for some new experiments.

June 1 (Friday) Canceled--Stryker Jury duty .

June 8 (Friday, 10:00-11:30 in HSW-701) Matt Caywood will present findings of his area 21a experiments. Then at 11:00, plan new lab jobs with Sheri.

June 11 (Monday, 10:00-1:30 in HSE-810) Mouse users meet with marie to plot out husbandry for next 6 weeks.

June 19 (TUESDAY 9:00-10:30) . Discussion of ideas for plasticity experiments--Stryker will lead.

June 26 (TUESDAY 9:00-10:30) Sunil and Cris discuss new data on band-limited white noise measurements of responses in various modalities.

July 3 (TUESDAY 10:00-11:30) Canceled--Sorry unexpected conflict, and lots of people are away in any case.

July 10 (TUESDAY 9:00-10:30) Canceled--Stryker away.

July 17 (TUESDAY 9:00-10:30) Report from Cris and Masaaki on the Gordon Conference, plus brief discussion by Sunil of Mrsic-Flogel TD, Hofer SB, Ohki K, Reid RC, Bonhoeffer T, Hubener M. (2007) Homeostatic Regulation of Eye-Specific Responses in Visual Cortex during Ocular Dominance Plasticity. Neuron. 54:961-72.

July 24 (TUESDAY 9:00-10:30) .We will discuss M Ren, Y Yoshimura, N Takada, S Horibe, and Y Komatsu (2007) Specialized Inhibitory Synaptic Actions Between Nearby Neocortical Pyramidal Neurons. Science 316: 758

July 31 (TUESDAY 9:00-10:30) Canceled--Stryker away.

August 7 (Tuesday 9:00-10:30) Cris will present Micheva KD, Smith SJ. (2007) Array tomography: a new tool for imaging the molecular architecture and ultrastructure of neural circuits. Neuron 55:25.

August 14 (Tuesday 9:00-10:00) Stryker will discuss grant aims and Conte work. Finish by 10:00.

****August 16 (Tuesday 9:00-10:00 in HSW-701)**** Stryker will discuss grant aims. Finish by 10:00.

August 21 (Tuesday 9:00-10:30) Canceled--Stryker away.

August 28 (Tuesday 9:00-10:30) Patrick McQuillen and Sam Faillor will present experiments on hypoxia-ischemia

November 20 (Tuesday 9:00-10:30, HSE-810) SFN Reprise (if not held earlier) or Sunil will present his recent findings (if most draft figures are ready)

December 11 (Tuesday 9:00-10:30, HSE-810) Sunil will present recent findings (if not presented above). Review of final analyses for Cris's receptive field manuscript.


January 8 (Tuesday 9:00-10:30, HSE-810) Brendan Murphy practice talk about his thesis

January 9(Wednesday 9:00-10:30, HSE-810) Special meeting with our Santa Cruz friends

January 15 (Tuesday 9:00-10:30, HSE-810) Canceled--Stryker away

January 22 (Tuesday 9:00-10:30, HSE-810) Special meeting with the core group to discuss lab jobs only and look at a few new illustrations

January 29 ***(Tuesday 9:30-10:30, HSE-810)***Late Start*** Laminar-specific expression of various markers. Erik Ullian will come talk about some of his candidates, and Stryker will bring a Cliff Ragsdale poster

***Feb 6  WEDNESDAY 9:00-10:30, HSW-701 Abbreviated meeting about grant aims

***Feb 13  WEDNESDAY 9:00-10:30, HSW-701 Patrick will present the Macklis lab paper on cortical cells:  Tina Lai,Denis Jabaudon, Bradley J. Molyneaux, Eiman Azim,Paola Arlotta, Joao R.L. Menezes, and Jeffrey D. Macklis (2008) SOX5 Controls the Sequential Generation of Distinct Corticofugal Neuron Subtypes Neuron 57: 232-247

***Feb 18 MONDAY 9:00-10:30, HSW-701

Cris will present two new papers on Satb2 and cortical development:
Alcamo et al (2008)  Satb2 Regulates Callosal Projection Neuron Identity in the Developing Cerebral Cortex.  Neuron, Vol 57, 364-377, 07 February 2008

Britanova,et al (2008) Satb2 Is a Postmitotic Determinant for Upper-Layer Neuron Specification in the Neocortex.  Neuron, Vol 57, 378-392, 07 February 2008

***Feb 27 WEDNESDAY 9:00-10:30, HSW-701 Sunil practice talk.

***March 10  MONDAY 9:00-10:30, HSE-810 Cris will talk about his ideas for new experiments

March 18  Tuesday 9:00-10:30, HSE-810 Michael will talk about things he learned at the Salk.

March 25  Tuesday 9:00-10:30, HSE-810 Canceled--Stryker away

April 1  Tuesday 9:00-10:30, HSE-810Sebastian Espinosa from Liqun Luo's lab at Stanford will give us an informal seminar about his work on MADM based analysis of cell lineage and gene function in the mouse nervous system. Lab lunch afterward.

April 8  Tuesday 9:00-10:30, HSE-810 Canceled--Stryker on vacation

April 15  Tuesday 9:00-10:30, HSE-810 Canceled--Stryker on vacation

April 22  Tuesday 9:00-10:30, HSE-810 Copenhagen will discuss possible experiments on the melanopsin retinal ganglion cells.

April 29  Tuesday 9:00-10:30, HSE-810We will discuss two recent papers:
Maya Vetencourt, J.F. et al. and Maffei, L. (2008) The antidepressant fluoxetine restores plasticity in the adult visual cortex.  Science 320:385-388.  doi:10.1126/science.1150516

May 20  Tuesday 9:00-10:30, HSE-810 Review our SfN abstracts. Megumi willl lead discussion of papers on homeostasis, including other papers on dark-rearing: Arianna Maffei and Gina G. Turrigiano (2008) Multiple Modes of Network Homeostasis in Visual Cortical Layer 2/3.  The Journal of Neuroscience  28:4377-4384.  doi:10.1523/jneurosci.5298-07.2008

May 27  Tuesday 9:00-10:30, HSE-810 A compact fast-scan 2-photon microscope: Dejan Vučinić and Terrence J. Sejnowski (2007) A Compact Multiphoton 3D Imaging System for Recording Fast Neuronal Activity.  PLoS ONE. 2007; 2(8): e699.. doi: 10.1371/journal.pone.0000699. PMCID: PMC1933593

June 3, 10  Tuesday 9:00-10:30, HSE-810 Canceled

June 17  Tuesday 9:00-10:30, HSE-810 Melinda progress report

June 24  Tuesday 9:00-10:30, HSE-810 Canceled--Stryker away

July 1  Tuesday 9:00-10:30, HSE-810 Torkel Hafting-Fyhn visit and informal talk

July 8  Tuesday Canceled--Stryker away

July 15  Tuesday 9:00-10:30, HSE-810 Anna Molofsky will talk about her PhD work.

July 22  Tuesday 9:00-10:30, HSE-810 Greenberg, D. S., Houweling, A. R., et al. (2008). Population imaging of ongoing neuronal activity in the visual cortex of awake rats. Nat Neurosci 11: 749-751. Plus some discussion of equipment.

July 29  Tuesday 9:00-10:30, HSE-810 Matt Caywood progress report

August 5, 12, 19  Tuesday 9:00-10:30, HSE-810 These Lab Meetings are canceled because of vacations

August 26  Tuesday 9:00-10:30, HSE-810 Dan Darcy review of his Ph.D. work (tentative).

September 2  Tuesday 9:00-10:00, HSE-810 Discussion of some technology issues.

September 9  Tuesday 9:00-10:30, HSE-810 Melinda will present. Sayaka Sugiyama, Ariel A. Di Nardo, Shinichi Aizawa, Isao Matsuo, Michel Volovitch, Alain Prochiantz, and Takao K. Hensch Experience-Dependent Transfer of Otx2 Homeoprotein into the Visual Cortex Activates Postnatal Plasticity Cell, Vol 134, 508-520, 08 August 2008

September 12  Friday 9:00-10:00, HSE-810 Megumi will present a practice job talk for the lab, and hope for criticism.

September 16 and 23  Tuesday Canceled--stryker away

September 30  Tuesday 9:00-10:30, HSE-810 open.

October 7  Tuesday 9:00-10:30, HSE-810 We will discuss lab jobs and two recent Bonhoeffer lab papers:

Tara Keck, Thomas D Mrsic-Flogel1, Miguel Vaz Afonso, Ulf T Eysel, Tobias Bonhoeffer & Mark Hübener Massive restructuring of neuronal circuits during functional reorganization of adult visual cortex Nature Neuroscience Published online: 31 August 2008 | doi:10.1038/nn.2181

October 14 Tuesday Canceled--stryker away October 10-20.

October 21  Tuesday 9:00-10:30, HSE-810 Open. We will do the Lohmann & Bonhoeffer paper that we did not finish it on October 7. Lohmann, C. and Bonhoeffer, T. (2008). A role for local calcium signaling in rapid synaptic partner selection by dendritic filopodia. Neuron 59: 253-260.

October 28  Tuesday 9:00-10:30, HSE-810 We will discuss together (since it is too late to ask anyone to lead) a preview in Neuron concerning one form of synaptic scaling: Rachel Groth and R.Y. Tsien write about A Role for Retinoic Acid in Homeostatic Plasticity in Neuron 23 October, 2008 Volume 60, Issue 2. They discuss Jason Aoto, Christine I. Nam, Michael M. Poon, Pamela Ting, Lu Chen (2008) Synaptic Signaling by All-Trans Retinoic Acid in Homeostatic Synaptic Plasticity NeuronVolume 60, Issue 223 October 2008, Pages 308-320.

November 4  Tuesday 9:00-10:30, HSE-810 ELECTION DAY! Vote early and often! Neuroscience Poster Review for Sunil's and Melinda's posters.

November 11  Tuesday 9:00-10:30, HSE-810 Review of talks & posters not to be missed at SFN meeting.

November 18  Tuesday 9:00-10:30, HSE-810 Canceled--SFN.

November 25  Tuesday 9:00-10:30, HSE-810 Live, from New York, Taro Toyoizumi will present some ofhis recent modeling work on the mechanisms of activity-dependent plasticity. At the end we will review some highlights from SfN.

December 2  Tuesday 9:00-10:30, HSE-810 Continmuation of modeling discussion with Ken and Taro.

December 9  Tuesday 9:00-10:30, HSE-810 Training.

December 16  Tuesday 9:00-10:30, HSE-810 Alan Litke and some of his Santa Cruz colleagues will discuss high-density multi-site cortical recording usinging silicon probes.

December 23  Tuesday 9:00-10:30, HSE-810 No lab meeting--Christmas Holiday

December 30  Tuesday 9:00-10:30, HSE-810 No lab meeting--Christmas Holiday